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  • S-Acetyl-L-Glutathione
  • S-Acetyl-L-Glutathione
  • S-Acetyl-L-Glutathione
  • S-Acetyl-L-Glutathione
S-Acetyl-L-GlutathioneS-Acetyl-L-GlutathioneS-Acetyl-L-GlutathioneS-Acetyl-L-GlutathioneS-Acetyl-L-Glutathione

S-Acetyl-L-Glutathione

  • Product Item : CAS No.: 3054-47-5
  • Category: Featured Products
  • Assay: 98%~101%
  • Appearance: White or Off white crystalline powder
  • Synonym: N5-((R)-3-(Acetylthio)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine, SAG
  • Molecular weight: 349.36
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Product Name: S-Acetyl-L-Glutathione

CAS No.: 3054-47-5

Appearance: White or Off white crystalline powder

Molecular weight: 349.36

Assay: 98%~101%

Synonym: N5-((R)-3-(Acetylthio)-1-((carboxymethyl)amino)-1-oxopropan-2-yl)-L-glutamine, SAG



S-Acetyl Glutathione penetrates into the mitochondrial membrane, helps maintain its integrity and function, and crosses the blood-brain barrier, allowing it to directly detoxify and protect the brain. Acetylated glutathione greatly improves its ability to remain intact in the intestine and allows higher concentrations to be absorbed into the bloodstream, better anti-aging.


What is S-Acetyl L-Glutathione?

S-Acetyl glutathione is the acetylation product of reduced glutathione. The acetyl group is connected to the sulfur atom of cysteine to protect the molecule from oxidation in the digestive tract and prevent the decomposition of glutathione. , So that it can enter cells through the intestine and be directly absorbed. When the acetyl glutathione enters the cell, the acetyl group is degraded and removed, and the glutathione returns to its free form to play a role in the cell. On the other hand, there is no unpleasant sulfhydryl taste, which can quickly increase the level of reduced glutathione in the cell without increasing energy consumption. Compared with glutathione, acetyl glutathione is more stable in plasma, and has also been shown to be more effective in supplementing glutathione cell levels lacking due to viral infections.

The markers of oxidative stress and inflammation are the intracellular measurement of reduced glutathione

The role of tools. Reduction of oxidative stress markers is a measure of the effectiveness of reduced glutathione supplementation

A pilot study on 6 patients used oxidative stress markers to evaluate the effects of two dosage forms of glutathione: intravenous glutathione and oral acetyl glutathione for one week, with a dose of 1400 mg.

The researchers concluded that oral acetyl glutathione is equivalent to an equivalent dose of intravenous glutathione

(MICHAEL ASH published in REVIEWS in 2011, please refer to the website: http://www.clinicaleducation.org/resources/reviews/oral-glutathione-equivalent-to-iv-therapy/


Function

1) Anti-Aging and Easily Absorbed by Body

S-Acetyl L-Glutathione is a widely used glutathione and is a derivative and development of reduced glutathione. Acetylation refers to the process of transferring an acetyl group to a side chain group of an amino acid, and acetylation of glutathione is usually the attachment of an acetyl group to an active sulfur atom. S-Acetyl Glutatione is a form of glutathione that is more stable and easily absorbed by body than other forms on the market.

S-Acetyl Glutathione penetrates into the mitochondrial membrane, helps maintain its integrity and function, and crosses the blood-brain barrier, allowing it to directly detoxify and protect the brain. Acetylated glutathione greatly improves its ability to remain intact in the intestine and allows higher concentrations to be absorbed into the bloodstream, better anti-aging.


2) Protect Liver

S-Acetyl L-Glutathione is the most effective glutathione variant currently on the market. Glutathione is one of the most potent antioxidants that is naturally produced by the body ( and the only one that is intracellular ) and it has been shown to neutralize free radicals, detoxify the liver, and to improve the functioning of the immune system.

S-Acetyl L-Glutathione is an altered form with an attached acetyl function group. This greatly improves its ability to remain intact in the gut and allows a greater concentration to be absorbed into the bloodstream where it can take effect.It is a form of glutathione which is more stable in the human intestine and more easily absorbed by the body than other forms on the market.


Features
1. S-Acetyl-L-Glutathione is the major endogenous antioxidant produced by the cells, participating directly in the neutralization of free radicals and reactive oxygen compounds, as well as maintaining exogenous antioxidants such as vitamins C and E in their reduced (active) forms.
2.Through direct conjugation, it detoxifies many xenobiotics (foreign compounds) and carcinogens, both organic and inorganic. This includes heavy metals such as mercury, lead, and arsenic.
3. S-Acetyl-L-Glutathione is essential for the immune system to exert its full potential, e.g., (1) modulating antigen presentation to lymphocytes, thereby influencing cytokine production and type of response (cellular or humoral) that develops, (2) enhancing proliferation of lymphocytes, thereby increasing magnitude of response, (3) enhancing killing activity of cytotoxic T cells and NK cells, and (4) regulating apoptosis, thereby maintaining control of the immune response.

4.It plays a fundamental role in numerous metabolic and biochemical reactions such as DNA synthesis and repair, protein synthesis, prostaglandin synthesis, amino acid transport, and enzyme activation. Thus, every system in the body can be affected by the state of the glutathione system, especially the immune system, the nervous system, the gastrointestinal system and the lungs.


Packaging Details

25 kg/drum, Net weight: 25kg, Gross weight: 28kg



Specification


ITEMS

SPECIFICATIONS

Identification

Positive

Appearance

White or Off white

crystalline powder

Lose on drying

≤0.5%

Residue on ignition

≤0.2%

Total Heavy metals

≤10ppm

Ammonium

≤200ppm

Chloride

200ppm

Sulfate

300ppm

Iron

10ppm

Acetone

0.2%

Assay (S-Acetyl-L-Glutathione)

98.0%~101%

GSH

1.0%



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