Fisetin

Product Name: Fisetin

CAS NO.: 528-48-3

Aassay: Fisetin 10%,40%,50%,70%,80%,85%,95%,98%

Botanical Name: Cotinus coggygria, smoke tree

Part Used: Branch

Chemical formula: C15H10O6

Other Names: Cotinin (not to be confused with Cotinine), 5-Deoxyquercetin, Superfustel, Fisetholz, Fietin, Fustel, Fustet, Viset, Junger fustik, 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxychromen-4-one

Product Description:

Fisetin is an unique botanical polyphenol and flavonoid found in a wide variety of plants, fruits and vegetables including strawberries, apples, persimmons, onions and cucumbers. Fisetin is a plant pigment, imparting many fruits and vegetables, such as strawberries, with their characteristic color and appearance. Fisetin has a very similar molecular structure to the more popular plant flavonoid and dietary supplement Quercetin. Unlike Quercetin, however, Fisetin is a senolytic and perhaps one of the most powerful senolytics known.

Function:

1. Fisetin can inhibit prostaglandin

2. Fisetin can be used to improve rheumatism, dysentery, gastrological, hernia, abdominal distension, toothache,traumatic injures, and skin ulcer in clinical;

3. Fisetin can be used as anti-inflammatory and antiproliferative;

Pharmacology:

1. Inhibition of prostaglandin: It can inhibit the formation of prostatic cords in 3T3 mouse fibrocytes transformed by methylcholanthracene, and the half effective inhibitory concentration (ID50) is 42.0UM.

2. Enzyme inhibition: It can inhibit the whole sugar reductase in the rat lens, and the half effective inhibition concentration is 10-6M

3. Spasmolytic: The antispasmolytic effect of acetylcholine was 166% of that of papaverine in small intestine specimens of mice.

4. In animal studies, a team of Japanese and American researchers found that urushetin, found in vegetables and fruits, improves memory.